If you are using the "Windows Aero" color scheme in Vista, which is the default color scheme, Windows seems to have problems rendering the Visual Studio UI.
I’ve noticed this problem when you run the solution and come back to Visual Studio after closing the solution. Vista can’t paint the portions of the screen occupied by the Visual Studio windows when the solution was being executed(like Command Window, Watch Window etc.). When you scroll up/down it’ll just paint the screen white. You’ll have to minimize and maximize Visual Studio to get it back to normal state!
If you change the color scheme to "Windows Vista Basic" it doesn’t seem to have any problems. Right click on the desktop and select "Personalization". Navigate to "Window Color and Appearance" ->"Open classic appearance properties for more color options". Select "Windows Vista Basic" and click Ok to change the color scheme. Haven’t tried this fix with other color schemes though.